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Benzodiazepines Direct ELISA Kit
Product Benzodiazepines Direct ELISA Kit
Catalog Number BQ 214-096
Quantity 96 Well Plate
Sample Type Whole Blood, serum, plasma, urine
Description
The Benzodiazepines Direct ELISA Kit is a sensitive in-vitro test to detect the presence of Benzodiazepines in samples such as whole blood, serum, plasma and urine. Benzodiazepines are a class of widely prescribed central nervous system depressant drugs with sedative, muscle relaxant and anti-convulsant activities. Chronic use does result in moderate dependence and tolerance to the drug. The use of alcohol in conjunction with the benzodiazepines has been shown to have a greater suppressive effect to the central nervous system than that attributable to either chemical alone. Benzodiazepines are usually administered orally and are absorbed rapidly. The metabolism of Benzodiazepines is mainly in the liver and excreted in the urine as a variety of structurally related metabolites. Metabolic similarities include removal of substituents from the B ring of the 1,4 benzodiazepines and alpha hydroxylation of the triazolobenzodiazepines, hydroxylation of the 3 position carbon of the B ring and conjugation of hydroxylated metabolites followed by urinary excretion as glucuronides.
Species Human